業績一覧
2015年
- Invest Ophthalmol Vis Sci. 2015 Jan 20;56(2):1051-62. doi: 10.1167/iovs.14-15619.
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M.
- Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
- Stem Cells. 2015 May 33(5):1543-53. doi: 10.1002/stem.1960.
Sun J, Mandai M, Kamao H, Hashiguchi T, Shikamura M, Kawamata S, Sugita S, Takahashi M.
- Protective effects of human iPS-derived retinal pigmented epithelial cells in comparison with human mesenchymal stromal cells and human neural stem cells on the degenerating retina in rd1 mice.
- Curr Eye Res. April 16, 2015. (doi:10.3109/02713683.2015.1038359)
Maekawa Y., Onishi A., Matsushita K., Koide N., Mandai M., Suzuma K., Kitaoka T., Kuwahara A., Ozone C., Nakano T., Eiraku M., Takahashi M.
- Optimized Culture System to Induce Neurite Outgrowth From Retinal Ganglion Cells in Three-Dimentional Retinal Aggregates Differentiated From Mouse and Human Embryonic Stem Cells.
2014年
- Stem Cell ReportsVol. 2(2):205-218., 2014
Hiroyuki Kamao, Michiko Mandai, Satoshi Okamoto, Noriko Sakai, Akiko Suga, Sunao Sugita, Junichi Kiryu, and Masayo Takahashi.
- Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application.
- Clinical Ophthalmology Volume 2014:8 Pages 435-440, 2014/2/24
Masako Kuroda, Yasuhiko Hirami, Masayuki Hata, Michiko Mandai, Masayo Takahashi, Yasuo Kurimoto.
- Intraretinal hyperreflective foci on spectral-domain optical coherence tomographic images of patients with retinitis pigmentosa
- PLoS ONE 9(4): e94556. doi:10.1371, 2014
Suga A, Sadamoto K, Fujii M, Mandai M, Takahashi M.
- Proliferation Potential of Müller Glia after Retinal Damage Varies between Mouse Strains.
- Stem Cell Reports 2(5):662-674,2014
Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamoto, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo Takahashi.
- Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice.
- Invest Ophthalmol Vis Sci. 2015 Jan 20;56(2):1051-62. doi: 10.1167/iovs.14-15619. .
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M.
- Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
2013年
- Stem Cells 31:1149-59, 2013
Homma K, Okamoto S, Mandai M, Gotoh N, Rajasimha HK, Chang YS, Chen S, Li W, Cogliati T, Swaroop A, Takahashi M.
- Developing Rods Transplanted into the Degenerating Retina of Crx- knockout Mice Exhibit Neural Activity Similar to Native Photoreceptors.
- Nature Communications Volume: 4, Article number: 1406,doi:10.1038/ncomms2420, Published 29 2013
Satoshi Nojima, Toshihiko Toyofuku, Hiroyuki Kamao, Chie Ishigami, Jun Kaneko, Tatsusada Okuno, Hyota Takamatsu, Daisuke Ito, Sujin Kang, Tetsuya Kimura, Yuji Yoshida, Keiko Morimoto, Yohei Maeda, Atsushi Ogata, Masahito Ikawa, Eiichi Morii, Katsuyuki Aozasa, Junichi Takagi, Masayo Takahashi & Atsushi Kumanogoh.
- A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration
2012年
- Jpn J Ophthalmol. 2012, in press. [Epub ahead of print]
Kawazoe Y, Sugita S, Yamada Y, Akino A, Miura K, Mochizuki M.
- Psoriasis Triggered by Infliximab in a Patient with Behçet’s Disease.
- Invest Ophthalmol Vis Sci. 2012;53:7299-7309.
Imai A, Sugita S, Kawazoe Y, Horie S, Yamada Y, Keino H, Maruyama K, Mochizuki M.
- Immunosuppressive properties of regulatory T cells generated by incubation of peripheral blood mononuclear cells with supernatants of human RPE cells.
- Jpn J Ophthalmol 2012; 56: 529-535.
Ogawa M, Sugita S, Shimizu N, Watanabe K, Nakagawa I, Mochizuki M.
- Evaluation of a broad-range real-time PCR assay for detection of bacterial DNA in ocular samples of infectious endophthalmitis.
- ProgRetin Eye Res. 2012. doi:pii: S1350-9462(12)00072-9. [Epub ahead of print]
Mochizuki M, Sugita S, Kamoi K.
- Immunological Homeostasis of the Eye.
- Invest Ophthalmol Vis Sci. 17;53(11):7183-93.2012
Vassilev VS, Mandai M, Yonemura S, Takeichi M.
- Loss of N-cadherin from the endothelium causes stromal edema and epithelial dysgenesis in the mouse cornea.
- Graefes Arch ClinExpOphthalmol. 250:391-398. 2012
Sugita S, Kamoi K, Ogawa M, Watanabe K, Shimizu N, Mochizuki M.
- Detection of Candida &Aspergillus species DNA using broad-range real-time PCR for fungal endophthalmitis.
- Exp Eye Res. 94:32-40. 2012
Kawazoe Y, Sugita S, Keino H, Yamada Y, Imai A, Horie S, Yamagami S, Mochizuki M.
- Retinoic acid from retinal pigment epithelium induces T regulatory cells.
- Invest Ophthalmol Vis Sci. 53:959-966. 2012
Tu Z, Li Y, Smith D, Doller C, Sugita S, Chan CC, Qian S, Fung J, Caspi RR, Lu L, Lin F.
- Myeloid suppressor cells induced by retinal pigment epithelial cells inhibit autoreactive T-cell responses that lead to experimental autoimmune uveitis.
- Graefes Arch ClinExpOphthalmol.in press [Epub ahead of print] 2012,
Ogawa M, Sugita S, Watanabe K, Shimizu N, Mochizuki M.
- Novel diagnosis of fungal endophthalmitis by broad-range real-time PCR detection of fungal 28S ribosomal DNA.
- Invest Ophthalmol Vis Sci. 53:3827-33. 2012
Nagata K, Maruyama K, Uno K, Shinomiya K, Yoneda K, Hamuro J, Sugita S, Yoshimura T, Sonoda KH, Mochizuki M, Kinoshita S.
- Simultaneous Analysis of Multiple Cytokines in the Vitreous of Patients with Sarcoid Uveitis.
- Invest Ophthalmol Vis Sci. 53:4692-4698. 2012
Sugita S, Shimizu N, Watanabe K, Ogawa M, Maruyama K, Usui N, Mochizuki M.
- Virological Analysis in Patients with Human Herpes Virus 6 (HHV-6)-Associated Ocular Inflammatory Disorders.
- Ophthalmology.in press. [Epub ahead of print]2012
Kojima K, Maruyama K, Inaba T, Nagata K, Yasuhara T, Yoneda K, Sugita S, Mochizuki M, Kinoshita S.
- The CD4/CD8 Ratio in Vitreous Fluid Is of High Diagnostic Value in Sarcoidosis.
- Arthritis Research & Therapy. 2012 14:R99
Sunao Sugita, Yuko Kawazoe, Ayano Imai, Yukiko Yamada, Shintaro Horie and Manabu Mochizuki
- Inhibition of Th17 differentiation by anti-TNFalpha therapy in uveitis patients with Behcet’s disease
- Stem Cells Translational Medicine. 2012
Zi-Bing Jin, Satoshi Okamoto, Ping Xiang and Masayo Takahashi
- Integration-Free Induced Pluripotent Stem Cells Derived from Retinitis Pigmentosa Patient for Disease Modeling
- Stem Cells. 2012 8.
West EL, Gonzalez-Cordero A, Hippert C, Osakada F, Martinez-Barbera JP, Pearson RA, Sowden JC, Takahashi M, Ali RR.
- Defining the Integration Capacity of ES Cell-Derived Photoreceptor Precursors.
- Cell Medicine 2012
Michiko Mandai, Kohei Homma, Satoshi Okamoto, Chikako Yamada, Akane Nomori, Masayo Takahashi.
- Adequate time window and environmental factors supporting retinal graft cell survival in rd mice.
- PLoS ONE. 7(2): e31036,2012
Hosono K, Ishigami C, Takahashi M, Park DH, Hirami Y, Nakanishi H, Ueno S, Yokoi T, Hikoya A, Fujita T, Zhao Y, Nishina S, Shin JP, Kim IT, Yamamoto S, Azuma N, Terasaki H, Sato M, Kondo M, Minoshima S, Hotta Y.
- Two Novel Mutations in the EYS Gene Are Possible Major Causes of Autosomal Recessive Retinitis Pigmentosa in the Japanese Population.
- PLoS ONE. 7(5): e37342 ,2012
Takuya Kuroda, Satoshi Yasuda, Shinji Kusakawa, Naoya Hirata, Yasunari Kanda, Kazuhiro Suzuki, Masayo Takahashi, Shin-Ichi Nishikawa, Shin Kawamata, Yoji Sato
- Highly Sensitive In Vitro Methods for Detection of Residual Undifferentiated Cells in Retinal Pigment Epithelial Cells Derived from Human iPS Cells
2011年
- Nihon Ganka Gakkai Zasshi. 115(10):916-23.Japanese, 2011
PMID: 22117325 [PubMed - indexed for MEDLINE] Related citations
Kuroda M, Hirami Y, Nishida A, Jin ZB, Ishigami C, Takahashi M, Kurimoto Y.
- A case of Oguchi disease with disappearance of golden tapetal-like fundus reflex after vitreous resection.
- CNS Neurol Disord Drug Targets. 10(4):419-32. [Review], 2011
Osakada F, Takahashi M.
- Neural induction and patterning in Mammalian pluripotent stem cells.
- Doc Ophthalmol 123:127-33,2011
Sonoyama H, Shinoda K, Ishigami C, Tada Y, Ideta H, Ideta R, Takahashi M, Miyake Y.
- Oguchi disease masked by retinitis pigmentosa.
- Invest Ophthalmol Vis Sci. 52(12) 8785-90, 2011
Satoshi Okamoto, Masayo Takahashi
- Induction of Retinal Pigment Epithelial cell
- Nat Methods. 2011 3. [Epub ahead of print]
Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka KI, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S.
- A more efficient method to generate integration-free human iPS cells.
2010年
- PLoS One. 10;6(2):e17084,2011
Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M.
- Modeling retinal degeneration using patient-specific induced pluripotent stem cells.
- Cell Transplant. 19(1):9-19,2010
Mandai M, Ikeda H, Jin ZB, Iseki K, Ishigami C, Takahashi M.
- Use of lectins to enrich mouse ES-derived retinal progenitor cells for the purpose of transplantation therapy.
2009年
- Jpn J Ophthalmol 53:396-407,2009
Yasuhiko Hirami, Michiko Mandai, Masayo Takahashi, Satoshi Teramukai, Harue Tada, and Nagahisa Yoshimura.
- Association of Clinical Characteristics with Disease Subtypes,Initial Visual Acuity, and Visual Prognosis in Neovascular Age-Related Macular Degeneration.
- Jpn J Ophthalmol 53:433-444,2009
Kumagai K, Oishi M, MFujihara M, Takahashi M, and Kurimoto Y.
- Sub-Tenon’s Injection of Triamcinolone for Optic Disc Neovascularization in a Patient with Retinitis Pigmentosa.
- Nature Protocols,4, 811-824 ,2009
Fumitaka Osakada, Hanako Ikeda, Yoshiki Sasai, Masayo Takahashi
- Stepwise differentiation of pluripotent stem cells into retinal cells.
- Neurosci Lett.458:126-131,2009
PMID: 19379795
Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H, Yoshimura N, Takahashi M.
- Generation of retinal cells from mouse and human induced pluripotent stem cells.
- Mol Vis. 15:523-533,2009
PMID: 19279690
Jin ZB, Hirokawa G, Gui L, Takahashi R, Osakada F, Hiura Y, Takahashi M, Yasuhara O, Iwai N.
- Targeted deletion of miR-182, an abundant retinal microRNA.
- J Neurosci Res. 87:2175-2182,2009
Homma K, Osakada F, Hirami Y, Jin ZB, Mandai M, Takahashi M.
- Detection of localized retinal malfunction in retinal degeneration model using a multielectrode array system.
2008年
- J Med Genet.45:465-472, 2008.
Jin ZB, Mandai M, Yokota T, Higuchi K, Ohmori K, Ohtsuki F, Takakura S, Itabashi T, Wada Y, Akimoto M, Ooto S, Suzuki T, Hirami Y, Ikeda H, Kawagoe N, Oishi A, Ichiyama S, Takahashi M, Yoshimura N, Kosugi S.
- Identifying pathogenic genetic background of simplex or multiplex retinitis pigmentosa patients: a large scale mutation screening study.
- Invest Ophthalmol Vis Sci. 49-9:3799-3805, 2008
Zi-Bing Jin, Michiko Mandai, Kohei Homma, Chie Ishigami, Yasuhiko Hirami, Nobuhisa Nao-i, and Masayo Takahashi.
- Allelic Copy Number Variation in FSCN2 Detected Using Allele-Specific Genotyping and Multiplex Real-Time PCRs.
- Nature Biotechnology. 26:215-224,2008
Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M.
- Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells.
- Am J Ophthalmol 145:687-694,2008
Murakami T, Akimoto M, Ooto S, Suzuki T, Ikeda H, Kawagoe N, Takahashi M, Yoshimura N.
- Association Between Abnormal Autofluorescence and Photoreceptor Disorganization in Retinitis Pigmentosa.
2007年
- Biochemical and Biophysical Research Communications. 363:292-296,2007
Oishi A, Nagai T, Mandai M, Takahashi M, Yoshimura N.
- The effect of dendritic cells on the retinal cell transplantation.
- Cell Transplantation. 16:493-503, 2007
Suzuki T, Akimoto M, Imai H, Ueda Y, Mandai M, Yoshimura N, Swaroop A, Takahashi M.
- Chondroitinase ABC Treatment Enhances Synaptogenesis Between Transplamt and Host Neurons in Model of Retinal Degeneration.
- Am J Ophthalmol. 144:475-477, 2007
Oishi A, Akimoto M, Kawagoe N, Mandai M, Takahashi M, Yoshimura N.
- Novel mutations in GRK1 gene in Japanese patients with Oguchi’s disease.
- J Neurosci. 27:4210-4219, 2007
Osakada F, Ooto S, Akagi T, Mandai M, Akaike A, Takahashi M.
- Wnt signaling promotes regeneration in the retina of adult mammals.
2006年
- Stem Cells. 24:2406-2411, 2006
Suzuki T, Mandai M, Akimoto M, Yoshimura N, Takahashi M.
- The simultaneous treatment of MMP-2 stimulants in retinal transplantation enhances grafted cell migration into the host retina.
- Proc Natl Acad Sci U S A. 20: 9554-9559, 2006
Ueno M, Matsumura M, Watanabe K, Nakamura T, Osakada F, Takahashi M,Kawasaki H, Kinoshita S, Sasai Y.
- Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.
2005年
- Invest Ophthalmol Vis Sci. 46:3411-3419, 2005
Akagi T. Akita J, Haruta M, Suzuki T, Honda Y, Inoue T, Yoshiura S, Kageyama R, Yatsu T, Yamada M, Takahashi M..
- Iris-derived cells from adult rodents and primates adopt photoreceptor specific phenotypes.
- Proc Natl Acad Sci U S A. 102:11331-11336, 2005
Ikeda H, Osakada F, Watanabe K, Mizuseki K, Haraguchi T, Miyoshi H, Kamiya D, Honda Y, Sasai N, Yoshimura N, Takahashi M, Sasai Y.
- Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.
- Retina. 25:54-58, 2005
Kimura T, Takahashi M, Takagi H, Kiryu J, Nishiwaki H, Tanabe T, Suzuma K, Oh H, Honda Y.
- Is Removal of Internal Limiting Membrane always Necessary during Stage 3 Idiopathic Macular Hole Surgery?
- J Biochem Biophys Methods. 62:251-258, 2005
Suzuki T, Akimoto M, Mandai M, Takahashi M, Yoshimura N.
- A new PCR-based approach for the preparation of RNA probe.
- Semin Ophthalmol. 20:11-15, 2005 Review.
Akagi T.
- Photoreceptors derived from adult iris tissue: prospects for retinal transplantation.
- Semin Ophthalmol. 20:17-23, 2005 Review.
Haruta M.
- Embryonic stem cells: potential source for ocular repair.
- Semin Ophthalmol. 20:25-30, 2005 Review.
Akimoto M.
- Transcriptional factors involved in photoreceptor differentiation.
- Humana Press Inc. In press.
Takahashi M, Haruta M.
- Derivation and characterization of lentoid bodies and RPE cells from monkey ES cells in vitro. Methods in Molecular Biology Series. Embryonic stem cells II: Methods and protocols. Ed. Krusad.
- Seminars in Ophthalmol. Vol.20, 2005
Takahashi M.
- Editorial. Guest editor.
2004年
- Molecular Vision. 10:923-932, 2004
Tanemura M, Miyamoto N, Mandai M, Kamizuru H, Ooto S, Yasukawa T, Takahashi M, Honda Y.
- The role of estrogen and aestrogen receptor in choroidal neovascularization.
- Invest Ophthalmol Vis Sci. 45:4570-4575, 2004
Akagi T, Mandai M, Ooto S, Hirami Y, Osakada F, Kageyama R, Yoshimura N, Takahashi M.
- Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue.
- J Biol Chem. 279:28492-28498, 2004
Akagi T, Inoue T, Miyoshi G, Bessho Y, Takahashi M, Lee JE, Guillemot F, Kageyama R.
- Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification.
- Proc Natl Acad Sci USA. 101:13654-13659, 2004
Ooto S, Akagi T, Kageyama R, Akita J, Mandai M, Honda Y, Takahashi M.
- Potential for neural regeneration after neurotoxic injury in the adult mammalian retina.
- Am J Ophthal. 137: 770-773, 2004
Nishijima K, Takahashi M, Akita J, Katsuta H, Tanemura M, Aikawa H, Mandai M, Takagi H, Kiryu J, Honda Y.
- Laser Photocoagulation of Indocyanine Green Angiographically Identified Feeder Vessels to Idiopathic Polypoidal Choroidal Vasculopathy.
- Biochem Biophys Res Commun. 316: 1-5, 2004
Amemiya K, Haruta M, Takahashi M, Kosaka M, Eguchi G.
- Adult human retinal pigment epithelial cells capable of differentiating into neurons.
- Invest Ophthalmol Vis Sci. 45:1021-1025, 2004
Haruta M, Sasai Y, Kawasaki H, Amemiya K, Ooto S, Kitada M, Suemori H, Nakatsuji N, Ide C, Honda Y, Takahashi M.
- In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells.
2003年
- Biochem Biophys Res Commun. 309:843-847, 2003
Suzuki T, Ooto S, Akagi T, Amemiya K, Igarashi R, Mizushima Y, Takahashi M.
- Effects of prolonged delivery of brain-derived neurotrophic factor on the fate of neural stem cells transplanted into the developing rat retina.
- Am J Ophthalmol, 136:1167-1170, 2003
Sasahara M, Noami S, Takahashi M, Honda Y.
- Optical coherence tomographic observations before and after macular hole formation secondary to laser injury.
- Invest Ophthalmol Vis Sci. 44:2689-2693, 2003
Ooto S, Haruta M, Honda Y, Kawasaki H, Sasai Y, Takahashi M.
- Induction of the Differentiation of Lentoids from Primate embryonic Stem Cells.
- Neurosci Lett.341:213-216, 2003
Akagi T, Haruta M, Akita J, Nishida A, Honda Y, Takahashi M.
- Different characteristics of rat retinal progenitor cells from different culture periods.
2002年
- Brain Res. 954:286-293, 2002
Akita J, Takahashi M, Hojo M, Nishida A, Haruta M, Honda Y
- Neuronal differentiation of adult rat hippocampus-derived neural stem cell transplanted into embryonic rat explanted retinas with retinoic acid pretreatment.
- Proc Natl Acad Sci U S A. 99:1580-5200, 2002
Kawasaki H, Suemori H, Mizuseki K, Watanabe K, Urano F, Ichinose H, Haruta M, Takahashi M, Yoshikawa K, Nishikawa SI, Nakatsuji N, Sasai Y.
- Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity.
2001年
- Nat Neurosci. 4:1163-1164, 2001
Haruta M, Kosaka M, Kanegae Y, Saito I, Inoue T, Kageyama R, Nishida A, Honda Y, Takahashi M.
- Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue.
- Brain Res. 920:217-221, 2001
Inatani M, Haruta M, Honjo M, Oohira A, Kido N, Takahashi M, Honda Y, Tanihara H.
- Upregulated expression of N-syndecan, a transmembrane heparan sulfate proteoglycan, in differentiated neural stem cells.
- Neurosci Lett. 306:57-60, 2001
Kurimoto Y, Shibuki H, Kaneko Y, Ichikawa M, Kurokawa T, Takahashi M, Yoshimura N.
- "Transplantation of adult rat hippocampus-derived neural stem cells into retina injured by transient ischemia.”
